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BetterHealthGuy Blogcasts

Jun 29, 2023

Why You Should Listen: 

In this episode, you will learn about the role of plasmalogens in cognition and overall health.

About My Guest:

My guest for this episode is Dr. Dayan Goodenowe.  Dayan Goodenowe, PhD is a neuroscientist and founder and CEO of Prodrome Sciences.  His research into the biochemical mechanisms of disease started in 1990.  His curiosity about the biochemistry of life is as insatiable today as it was over 30 years ago.  In those more than 30 years, Dr. Goodenowe invented and developed advanced bioinformatic technologies, designed and manufactured novel supplements, and identified biochemical prodromes of numerous diseases including Alzheimer’s disease and dementia, Parkinson’s disease, multiple sclerosis, autism, amyotrophic lateral sclerosis (ALS), schizophrenia, bipolar disorder, depression, and numerous cancers. 

Key Takeaways:

  • What are prodromes of disease and of health?
  • What are plasmalogens?
  • Where are plasmalogens high in the body?
  • What conditions do low plasmalogens contribute to?
  • What factors lead to lower than optimal plasmalogen levels?  How can endogenous production be optimized?
  • Are plasmalogens addressing root causes of cognitive decline or are they essentially shielding the body from their damaging effects?
  • How do plasmalogens impact amyloid precursor protein?
  • Can plasmalogens mitigate the potential contribution of ApoE4 to cognitive decline?
  • Do plasmalogens have a similar effect in SCI, MCI, dementia, and Alzheimer's?
  • How do plasmalogens impact cholinergic neuron function?
  • How do other phospholipids such as phosphatidylcholine fit into the plasmalogen conversation?
  • What is a healthy cholesterol level?
  • From a lipid optiminization perspective, what is an optimal diet?
  • Do plasmalogens play a role in traumatic brain injuries?
  • What is the ProdromeScan test?  Why are specific markers included?
  • What are ProdromeNeuro and ProdromeGlia plasmalogen precursors?

Connect With My Guest:

Related Resources:

Prodrome Sciences
25% off discount code BETTERHEALTH25

Interview Date:

June 23, 2023


To review a transcript of this show, visit

Additional Information:

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Disclosure: is an affiliate of Prodrome Sciences.


The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority.